Novel Tissue Scaffolding Technique Helps Build Large Organs

Source: Gen News

(BRISTOL, England) — Researchers say they have developed a new tissue scaffold technology that could one day enable the engineering of large organs. The team led by the Universities of Bristol and Liverpool has shown that it is possible to combine cells with a special scaffold to produce living tissue in the laboratory. It is hoped this can then be implanted into patients as a way of replacing diseased parts of the body.

Until now, the approach has generally been limited to growing small pieces of tissue, as larger dimensions reduce the oxygen supply to the cells in the center.

The scientists used cartilage tissue engineering as a model system for testing a new method of overcoming the oxygen limitation problem. They synthesized a new class of artificial membrane binding proteins that can be attached to stems cells. By attaching an oxygen-carrying protein, myoglobin, to the stem cells before they are used to engineer cartilage, they ensure that each cell has its own oxygen reservoir that it can access when the oxygen in the scaffold drops to dangerously low levels.

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By |June 17th, 2015|Uncategorized|0 Comments

Mayo Clinic Opens New Regenerative Center


(ROCHESTER, New York) — Local officials hope a new ultra-clean laboratory in the Mayo Clinic Center for Regenerative Medicine will help draw businesses in the burgeoning field.

“It is one of the only few places of its kind on the planet available to companies,” said Gary Smith, president of Rochester Area Economic Development Inc. “These are expensive facilities to build, and a lot of companies can’t afford that capital investment.”

Having opened its doors to visitors only last week, final touches were being applied Tuesday to the sensitive equipment during a tour of the Advanced Product Incubator.

The 3,000-square-foot laboratory and office space anchors half of the third floor of the Minnesota Biobusiness Center. Because the API is hoping to attract business to Rochester in addition to developing therapies within the clinic, the facility was jointly funded by RAEDI, the city of Rochester and Mayo Clinic.

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