Researchers Use Human Pluripotent Stem Cells to Grow Hair

(LA JOLLA, Ca.) —¬†Researchers from Sanford-Burnham Medical Research Institute (Sanford-Burnham) have used human pluripotent stem cells to generate new hair in bald mice. The study, published online in PLOS One¬†yesterday, represents the first step toward a cell-based treatment for people with hair loss. In the United States more than 40 million men and 21 million women are affected by hair loss.

The research team developed a protocol that coaxed human pluripotent stem cells to become dermal papilla cells. These are unique cells that regulate hair-follicle formation and growth cycle.

Alexey Terskikh, Ph.D., associate professor in the Development, Aging, and Regeneration Program at Sanford-Burnham, says the next step is to transplant the cells into humans.

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By |January 27th, 2015|Uncategorized|0 Comments

New Multiple Sclerosis Stem Cell Study Shows Improvements

(Evanston, Ill.) — Treatment with a form of stem cell transplantation in individuals with relapsing-remitting multiple sclerosis has demonstrated improvements in neurological disability, quality of life, and cognitive function. The new study, which appears in a recent issue of the Journal of the American Medical Association, did not show similar positive results for individuals with secondary progressive MS.

Numerous scientific teams have been exploring the use of stem cell transplantation for multiple sclerosis. A form known as hematopoietic stem cell transplantation (HSCT), which is the form used in this study and various others, involves giving patients an intravenous infusion of their own (autologous) stem cells that have been harvested from peripheral blood or bone marrow in an effort to reset immune system functioning.

The new study was conducted by Richard Burt, MD, of Northwestern University Feinberg School of Medicine, and his colleagues.

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By |January 26th, 2015|Multiple Sclerosis, Stem Cells|0 Comments